The objective of PASSOS (Personalised assessment of late health risks after exposure to ionising radiation and guidance for radiation applications in medicine) is the assessment of the risk of cancer and cardiovascular diseases after medical radiation exposure, considering individual factors. Treatment techniques of breast cancer therapy and cardiac diagnostic procedures are investigated. More...

Work packages

The project is divided into the following work packages:

  1. PASSOS Heart Study: Epidemiological study of cardiovascular risks after breast cancer therapy
  2. Dosimetry Breast Cancer Treatment Techniques: Whole-body dose distribution of different treatment techniques in breast cancer patients with good prognosis
  3. Dosimetry Heart Diagnostics: Whole-body dose distribution of different imaging modalities for diagnosis of heart diseases with good prognosis
  4. Personalised Risks: Personalised Risks for radiation induced late health effects
  5. Software


PASSOS: Risk models for assessment of long-term health risks after breast cancer radiotherapy

A major challenge in the estimation of long-term risks in breast cancer radiotherapy are the complex dosimetric relationships. In radiotherapy, high...
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Overview of PASSOS methodology

Overview of PASSOS methodology   Breast-cancer radiotherapy (RT) reduces the recurrence rates and improves patient survival. However, it also...
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Minimum breast distance largely explains individual variability in doses to contralateral breast from breast-cancer radiotherapy

Breast cancer is the most frequent cancer in women worldwide. Fortunately, its cure rates are high if diagnosed at an early stage. Commonly it is...
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Modern breast cancer radiation therapy and risks of secondary lung cancer and ischaemic heart diseases

Breast cancer is the most common cancer in women. In the last decades, the life expectancy of breast cancer patients increased substantially due to...
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Intended further developments

A lot has been achieved in PASSOS but new challenges and questions have arisen. The project is terminated end of 2016; still, further developments...
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Status (January 2017)

An overview of activities, analyses and achievements in PASSOS can be found following the links: WP 1: PASSOS Heart Study WP 2: Dosimetry Breast...
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Dr. Markus Eidemüller

Institute of Radiation Medicine
Helmholtz Zentrum München -
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)

Ingolstädter Landstraße 1
D-85764 Neuherberg

Tel. +49 89 3187-2801